First-line Therapy (7-10 days)

    PPI standard dose twice daily +

    Clarithromycin 500 mg twice daily +

    Amoxicillin 1 g twice daily

Second-line Therapy (10-14 days)

    PPI standard dose twice daily +

    Metronidazole 500 mg thrice daily or amoxicillin 1 g twice daily +

    Tetracycline 500 mg 4 times daily +

    Bismuth subcitrate 120 mg 4 times daily

Rescue Therapies

    PPI standard dose twice daily +

    Rifabutin 300 mg once daily +

    Amoxicillin 1g twice daily

    for 7 days

            or

    PPI standard dose twice daily +

    Amoxicillin 1g twice daily. +

    Levofloxacin 500 mg once daily for 7 days

            or

    PPI standard dose twice daily. +

    Amoxicillin 1g twice daily for 5 days

        followed by

    PPI standard dose twice daily +

    Clarithromycin 500 mg twice daily +

    Tinidazole 500 mg twice daily for 5 days

Reference: Eradication of Helicobacter pylori: A Clinical Update. Marco Romano, MD; Antonio Cuomo, MD Medscape General Medicine™ Gastroenterology Posted 02/17/2004